It is important to note that applying a blend to multiple edges at one time may yield different results than if you applied the blend to each edge individually. It is generally preferable to apply a blend to all edges of interest at the same time. For example, if you pick one edge and apply a fillet, and then repeat this for the remaining two edges of the corner of a box you get the following.
If instead you pick all three edges and apply a single fillet you get the following.
Note that defining a blend larger than an entire adjacent face can cause issues and should be done with caution.